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Emdogain
Emdogain is a recently introduced product that fools the body into forming
new bone, cementum, and attachment fibers. Technically, it is enamel matrix
proteins (amelogenins) that are taken from developing teeth in pigs. These
proteins are similar in all mammals, and humans do not recognize them
as foreign. There is also no chance of transmission of any bacteria or
virus by the proteins. In tooth development, the secretion of these proteins
onto the developing root surface precedes the formation of tooth attachment.
A similar action occurs when the proteins are placed on a root surface
that has lost bone and attachment from disease. When applied to the root
surface during surgery, these proteins assemble into an insoluble matrix
layer that promotes the attachment of mesenchymal cells. These cells produce
new matrix components and growth factors that participate in the regain
of tooth attachment. Emdogain also inhibits epithelial cell growth that
could interfere with proper tissue and bone reformation.
Please click on the images for a larger view.
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